Aquifex aeolicus tRNA ( N 2 , N 2 - Guanine ) - dimethyltransferase ( Trm 1 ) Catalyzes Transfer of Methyl Groups Not Only to

Takako Awai, Satoshi Kimura, Chie Tomikawa, Anna Ochi, Ihsanawati, Yoshitaka Bessho , Shigeyuki Yokoyama **, Satoshi Ohno, Kazuya Nishikawa, Takashi Yokogawa, Tsutomu Suzuki, and Hiroyuki Hori From the Department of Materials Science and Biotechnology, Graduate School of Science and Engineering, Ehime University, Bunkyo 3, Matsuyama, Ehime 790-8577, the Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8656, the Systems and Structural Biology Center, Yokohama Institute, RIKEN, Suehiro-cho 1-7-22, Tsurumi-ku, Yokohama, Kanagawa 230-0045, the RIKEN SPring-8 Center, Harima Institute, Kouto 1-1-1, Sayo, Hyogo 679-5148, the **Department of Biophysics and Biochemistry, Graduate School of Science, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-0033, the Department of Biomolecular Science, Faculty of Engineering, Gifu University, Yanagido 1-1, Gifu, Gifu 501-1193, and the Venture Business Laboratory, Ehime University, Bunkyo 3, Matsuyama, Ehime 790-8577, Japan